"How long 'til this hits?"
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(7/10/20 Note: "100% No Stress Day," despite being the first episode to be publicly shown of Close Enough, is not the first episode of the proper series, but instead the sixth. While that affects some of my assessments quite a bit, I still stand by my criticisms even if the context needs to be re-adjusted.)
(NOTE: In light of the fact that this episode has not been formally released, this review will operate under the assumption that you haven't seen the show. As such, there will be no major plot spoilers, but discussion of the show's general direction and the episode's plotting.)
On the plus side, no mistake can be made: this is a J.G. Quintel show, and that alone carries it a long way. Many of Regular Show's most crucial staff members have returned—including Minty Lewis, Calvin Wong, and Owen Dennis (now of Infinity Train fame)—and the distinct art style has been retained to loving effect. Truly, Close Enough is a more untethered version of Regular Show, no longer needing to mask getting high under transparent but creative implications and having the liberty to throw in as many utterances of "bitch" and "shit" as it wants... but that it's untethered isn't necessarily a better thing.